The film follows the true story of Dr. Dennis Slamon (played by Harry Connick, Jr.), who helped develop the breast cancer drug Herceptin, over the course of 8 years from 1988 to 1996. Dr. Slamon is a research doctor at UCLA Medical Center (Los Angeles), where he has developed the experimental drug Herceptin, which he believes will become a treatment for breast cancer. However, when the drug company stops funding for research, philanthropists, including Lilly Tartikoff (Angie Harmon) and Ronald Perelman (Joe Nemmers) help him continue tests of the drug. Funding was done with an initial donation from Perelman's Revlon charity, and continued over the years with the "Fire and Ice Ball" organized by Tartikoff.
Eventually the drug company funds the research and the drug goes through three trials before gaining approval from the FDA (Food and Drug Administration). Prior to the trials, the drug has a "mouse trial", with Nicole (Tammy Blanchard), a young mother with stage 4 cancer, receiving the drug first. Although her mother Elizabeth (Swoosie Kurtz) pleads with Dr. Slamon, Nicole is not included in the subsequent trials as she does not meet the protocols. The women in the trials, particularly the first trial, band together. They handle their disease and drug trial, with humor--Tish (Jennifer Coolidge), or with alternative therapy--Tina (Trudie Styler). The stories of Barbara (Bernadette Peters) and Ellie (Regina King) are followed throughout, as they go through the trials and eventual recovery. Some patients involved in the tests die, but ultimately Slamon's work with the drug changes the course of breast cancer treatment.
Watched this last night, oh my god this is an amazing movie tells the true story of Dr D Slamon, who discovered a drug to help breast cancer suffers. This tells you how much time he spent away from his family as he was commit to making this drug. Make sure you have hankies about as in some places its very sad. I recommend this to all!!!